Blebbistatin molecular weight
WebBuy (+)-Blebbistatin (CAS 1177356-70-5), a useful negative control for the active enantiomer, from Santa Cruz. Molecular Formula: C18H16N2O2, MW 292.3. Choose a Store Santa cruz biotechnology. Santa Cruz Animal Health ... Molecular Weight: 292.3. Molecular Formula: C 18 H 16 N 2 O 2. WebA cell-permeable biphenylylpentanoic acid compound that acts as a selective allosteric inhibitor of E2 ubiquitin-conjugating enzyme Cdc34 (IC 50 = 2.5 µM in a Sic1-SCF Cdc4 assay) without affecting the activities of E1 or E3 ligases. Reported to act by trapping a weak interaction between ubiquitin and the E2 donor ubiquitin-binding site and may serve as a …
Blebbistatin molecular weight
Did you know?
Web(±)-Blebbistatin (±)-Blebbistatin, CAS 674289-55-5, is a cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration & cytoKinesis in vertebrate cells.; ... Molecular Weight: 292.33. NACRES: NA.77. … WebBlebbistatin was discovered in 2003 and exhibits high affinity and selectivity for myosin-2. 167 Myosins from classes-1, -5, -10, but also smooth muscle myosin-2, are weakly or not affected by blebbistatin, whereas skeletal and nonmuscle myosin-2 are potently inhibited (IC 50 =0.5–2 μM). 168 The other enantiomer (+)-blebbistatin was found to ...
WebPreparing Stock Solutions for (S)-(-)-Blebbistatin. The following data is based on the product molecular weight 292.34. Batch specific molecular weights may vary from … WebThe following data is based on the product molecular weight 292.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
WebJun 13, 2005 · blebbistatin (CHEBI:75388) Affected organisms Not Available Chemical Identifiers UNII 8WII7624I5 CAS number Not Available InChI Key LZAXPYOBKSJSEX-GOSISDBHSA-N ... Molecular Weight 227868.56 Da. References. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data …
WebIn the presence of blebbistatin, the initial rapid fluorescence increase was followed by a quench phase (k obs = 0.03 s –1 at 7.5 μ m blebbistatin and 0.18 s –1 at 50 μ m blebbistatin) leading to a fluorescence level that is 5–10% lower than that of apoS1. Traces were normalized to their starting values.
WebMar 6, 2005 · Molecular motors play a central role in cytoskeletal-mediated cellular processes and thus present an excellent target for cellular control by pharmacological agents. Yet very few such compounds ... screening for women by ageWeb(±)-Blebbistatin is a selective inhibitor of myosin II ATPase activity; inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. ... *When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online). Citations for (± ... screening for west nile virusWebMolecular Weight: 292.33: Formula: C 18 H 16 N 2 O 2. CAS No. 856925-71-8: Storage: 3 years -20°C(in the dark) powder 2 years -80°C(in the … screening forceWebMay 30, 2012 · In vitro, blebbistatin inhibits vertebrate striated muscle and nonmuscle myosin II isoforms as well as Dictyostelium discoideum (Dd) myosin II by about 95%, with an IC 50 of 0.5–5 μM ().Vertebrate smooth muscle and Acanthamoeba myosin II are incompletely inhibited even at high blebbistatin concentrations. In vivo experiments … screening for you and your baby bookletWebMay 16, 2013 · Molecular weight. 292.34. Molecular formula. C 18 H 16 N 2 O 2. PubChem identifier. 3476986. Storage instructions. Store at +4°C. Store under desiccating conditions. ... -blebbistatin (ab120425), by ICC/IF. Decreased membrane expression of paxillin correlates with increased concentration of (+/-)-blebbistatin, as described in … screening forms pdfWebMolecular Formula. C 17 H 13 N 3 O 4. Formula Weight. 323.3. Purity. ≥98%. Formulation(Request formulation change) A crystalline solid. ... -Blebbistatin rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC 50 s = 0.5-5 µM), while poorly inhibiting smooth muscle ... screening form jicaWebPreparing Stock Solutions for (±)-Blebbistatin. The following data is based on the product molecular weight 292.34. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions. screening form in spanish